Thermo Fisher Scientific MRPL18 Polyclonal Antibody
Thermo Fisher Scientific의 MRPL18 Polyclonal Antibody는 인간 MRPL18 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot과 IHC(P) 실험에 적합하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 안정적인 장기 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–208 of Human MRPL18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549348 |
Product Specific Information
- Recommended positive controls: NT2D1, PC-3, U87-MG
- Predicted reactivity: Mouse (86%), Rat (84%), Rhesus Monkey (97%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA ratio, unlike prokaryotic ribosomes where this ratio is reversed. Prokaryotic ribosomes contain a 5S rRNA, which is absent in mammalian mitoribosomes. The proteins comprising the mitoribosome differ significantly among species, making sequence homology recognition difficult.
The MRPL18 gene encodes a 39S subunit protein belonging to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, including one that adds an extra amino acid near the N-terminus.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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