Thermo Fisher Scientific NAIF1 Polyclonal Antibody
NAIF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용 가능. 단백질 A로 정제된 액상 형태, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NAIF1, amino acids 3–85 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human NAIF1 is located on chromosome 9q34.11 and encodes a 327-amino-acid protein with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken, and frog, and shares no obvious homology to any known genes or proteins. NAIF1 is predominantly localized in the nucleus. Overexpression of NAIF1 inhibits cell growth and induces apoptosis, accompanied by a decrease in mitochondrial membrane potential and activation of caspase-3. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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