Thermo Fisher Scientific hnRNP M Recombinant Rabbit Monoclonal Antibody (JE64-62)
hnRNP M 단백질을 검출하기 위한 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. HEK293 세포에서 발현된 IgG 형 항체로 높은 특이성과 재현성 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunocytochemistry (ICC/IF) | 1:400 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE64-62 |
| Immunogen | Synthetic peptide within human HNRNPM aa 250–300/730 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2931163 |
Target Information
The hnRNP M gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These RNA-binding proteins form complexes with heterogeneous nuclear RNA (hnRNA) and are involved in pre-mRNA processing, mRNA metabolism, and transport. While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. The hnRNP M protein contains three quasi-RRM domains that bind RNA and functions as part of the N-acetylglucosamine-specific receptor, which may play a role in recycling immature GlcNAc-bearing thyroglobulin molecules. Multiple transcript variants are generated through alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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