Thermo Fisher Scientific DCLK1 Polyclonal Antibody
DCLK1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(P) 등에 사용 가능. Bovine, Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며 PBS 완충액에 0.01% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides from rat DCLK1: 1) MLELIEVNGTPGSQLSTPRS 2) PSPSPT-S*-PGSLRKQR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: HCT116, MiaCaCa cell lysate
- Cellular location: Cytoplasm
Target Information
DCAMKL1 (DCLK1) serine/threonine kinase, also known as doublecortin-like kinase 1, contains two N-terminal doublecortin domains that bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase, and a serine/proline-rich domain mediating protein-protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and microtubule polymerization independent of its kinase activity. It plays roles in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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