Thermo Fisher Scientific ZRANB2 Polyclonal Antibody
Thermo Fisher Scientific의 ZRANB2 Polyclonal Antibody는 인간 ZNF265 유래 합성 펩타이드로 제작된 Rabbit IgG 항체입니다. Western blot과 Immunocytochemistry에 적합하며, 비결합형 액상 형태로 제공됩니다. 핵 내 스플라이싱 인자 ZNF265 검출 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human ZNF265 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555154 |
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, mainly in transcriptional activation or repression.
ZNF265 (also known as ZRANB2, ZIS, ZIS1, or ZIS2) is a 330-amino acid protein belonging to the ZRANB2 family. It localizes to the nucleus and functions as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts, interfering with constitutive 5'-splice selection.
ZNF265 contains two RanBP2-type zinc fingers that mediate RNA-binding activity. Two isoforms, ZIS-1 and ZIS-2, arise from alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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