Thermo Fisher Scientific Complement C4b Polyclonal Antibody
Human Complement C4b 인식용 Rabbit Polyclonal Antibody로 Western blot 검증 완료. 비결합형 액상 형태이며, 고순도 친화 크로마토그래피 정제. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
- 판매단위
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Applications
- Western Blot (WB): Tested dilution 1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human Complement C4 beta chain (aa 21–70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term); -20°C (long term, avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913197 |
Product Specific Information
- Positive Control: Human serum
- Subcellular Location: Secreted
Target Information
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single-chain precursor that is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen–antibody complex and other complement components.
The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus.
This gene localizes to the MHC class III region on chromosome 6. Varying haplotypes exist, with individuals possessing 1–3 copies. Additionally, long and short forms are present due to a 6.4 kb endogenous HERV-K retrovirus in intron 9.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(PA5-119624_Complement_C4b_P0C0L5-1_Rabbit.svg)
(PA5-119624_Complement_C4b_P0C0L5-1_Rabbit_PDP.jpeg)
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