Thermo Fisher Scientific CD5 Monoclonal Antibody (L17F12), FITC, eBioscience

Applications

• Flow Cytometry (Flow): 5 µL (0.125 µg)/test
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Product Specifications

Additional Available Formats

• APC
• PE-Cyanine5
• PE-eFluor 610
• PerCP-Cyanine5.5
• Super Bright 436
• Super Bright 600
• Request custom conjugation

Product Specific Information

The L17F12 monoclonal antibody reacts with human CD5, a 67 kDa protein expressed by most thymocytes, mature T cells, and a subset of B cells. CD5 signaling activates T cells and mediates T-B cell interactions via CD72 binding, playing an important role in proliferation.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Pre-titrated and validated for flow cytometry using normal human peripheral blood cells
• Recommended Usage: 5 µL (0.125 µg) per 100 µL test volume (10⁵–10⁸ cells/test)
• Excitation: 488 nm
• Emission: 520 nm
• Laser: Blue Laser
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. It also reacts with a subset of activated B-cells and may regulate T-cell proliferation. CD5 is found on approximately 95% of thymocytes and 72% of peripheral blood lymphocytes, primarily in T-cell areas of lymph nodes. Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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