Thermo Fisher Scientific HDAC6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2-5 µg/mL

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Immunocytochemistry (ICC/IF)

2 - 5 µg/mL

-

Immunoprecipitation (IP)

Assay-Dependent

-

ChIP assay (ChIP)

1:20-1:1,000

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Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide made to an N-terminal portion of human HDAC6 (between amino acids 1-50) [UniProt Q9UBN7] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDAC6,uniProtId:Q9UBN7-1,ncbiNodeId:9606,antigenRange:1-50,antigenLength:1215,antigenImageFileName:PA1-41056_HDAC6_Q9UBN7-1_Rabbit.svg,antigenImageFileNamePDP:PA1-41056_HDAC6_Q9UBN7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2232920

Product Specific Information

Suggested positive control: antigen standard for HDAC6 (transient overexpression lysate), NIH-3T3 whole cell lysate.

Target Information

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.