Thermo Fisher Scientific RPS17 Monoclonal Antibody (2C7)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
EEIAIIPSKK LRNKIAGYVT HLMKRIQRGP VRGISIKLQE EERERRDNYV PEVSALDQEI IEVDPDTKEM LKLLDFGSLS NLQVTQPTVG MNFKTPRGPV

Target Information

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions.

Ribosomal Protein S17 (RPS17, RPS17L1, RPS17L2) is a 135 amino acid protein that is a component of the 40S subunit. Localized to the cytoplasm and expressed ubiquitously, RPS17 belongs to the S17e family of ribosomal proteins and functions in protein synthesis.

Mutations in the gene encoding RPS17 are associated with Diamond-Blackfan anemia (DBA), a rare congenital disorder characterized by defective differentiation of pro-erythroblasts. Like most ribosomal proteins, RPS17 exists as multiple processed pseudogenes scattered throughout the genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.