Thermo Fisher Scientific GBP5 Monoclonal Antibody (OTI8B12)
GBP5 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Western blot과 유세포분석에 적합. 인간 GBP5에 특이적이며, 액상 형태로 제공. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B12 |
| Immunogen | Full length human recombinant protein of GBP5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS (pH 7.3), with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723210 |
Target Information
The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins that function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs (hGBP1 to hGBP7). Human GBP1 and GBP2 have been shown to exhibit antiviral activity and regulate endothelial cell proliferation and invasion in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble, but not crystalline, inflammasome priming agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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