Thermo Fisher Scientific TRPM4 Polyclonal Antibody
상품 옵션 정보 | |||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA5116483 | - | Thermo Fisher Scientific PA5116483 TRPM4 Polyclonal Antibody 100 ul pk | 재고문의 | pk | 670,000원 | - | 737,000원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
Flow Cytometry (Flow)
1:50-1:100
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within human TRPM4 aa 1-50 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
TRPM4,
uniProtId:
Q8TD43-1,
ncbiNodeId:
9606,
antigenRange:
1-50,
antigenLength:
1214,
antigenImageFileName:
PA5-116483_TRPM4_Q8TD43-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-116483_TRPM4_Q8TD43-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901114
Product Specific Information
Positive controls: SK-Br-3 cell lysates, rat heart tissue, mouse small intestine tissue, MCF-7.
Target Information
Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. Mediates transport of monovalent cations (Na+, K+, Cs+, Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca2+ overload. Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization. Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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