Thermo Fisher Scientific TRPV4 Polyclonal Antibody
닭 TRPV4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. 합성 펩타이드를 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. TRPV4의 삼투압 감지 및 기계적 민감성 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | — |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | — |
| Miscellaneous PubMed (Misc) | — | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 1st cytoplasmic loop of chicken TRPV4 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPV4
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure.
It is a non-selective calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the TRP superfamily.
Mutations in the TRPV4 gene are associated with disorders such as Metatropic Dysplasia, Spondylometaphyseal Dysplasia (Kozlowski Type), and Hereditary Motor and Sensory Neuropathy Type IIC.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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