Thermo Fisher Scientific Parvalbumin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-0.3 µg/mL

-

Immunohistochemistry - Free Floating (IHC (Free))

-

View 1 publication 1 publication

Flow Cytometry (Flow)

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Published species

Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (GVDEFSTLVAES) corresponding to the C-terminus amino acids of PVALB (aa 99-110). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Parvalbumin,uniProtId:P20472-1,ncbiNodeId:9606,antigenRange:99-110,antigenLength:110,antigenImageFileName:PA5-18389_Parvalbumin_P20472-1_Goat.svg,antigenImageFileNamePDP:PA5-18389_Parvalbumin_P20472-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10977301

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

Target Information

Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.