Thermo Fisher Scientific OPHN1 Polyclonal Antibody
인간 OPHN1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200–1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공. 신경 시냅스 기능 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OPHN1. Recombinant protein control fragment (Product # RP-92171) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644988 |
Product Specific Information
Immunogen sequence:
RVTARRHKPI TISKRLLRER TVFYTSSLDE SEDEIQHQTP NGTITSSIEP PKPPQHPKLP IQRSGETDPG RKSPSRPILD GKLEPCPEVD VGKLVSRLQD GGTKITPK
Sequence identity:
- Mouse: 77%
- Rat: 74%
Target Information
Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function.
Critical for the stabilization of AMPA receptors at postsynaptic sites.
Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals.
Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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