Thermo Fisher Scientific AMOTL2 Polyclonal Antibody
AMOTL2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 IHC(P)에서 1:25–1:100 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제, PBS(glycerol 포함) 용액 형태로 제공. 연구용 전용 제품.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific AMOTL2 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human angiomotin like 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635775 |
Product Specific Information
This antibody detects endogenous levels of total AMOTL2 protein.
Target Information
AMOTL2 regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites and is required for proper actin filament architecture. It inhibits the Wnt/β-catenin signaling pathway, possibly by recruiting CTNNB1 to recycling endosomes and preventing its nuclear translocation. AMOTL2 participates in angiogenesis and may influence polarity, proliferation, and migration of endothelial cells. It selectively promotes FGF-induced MAPK activation through SRC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.