Thermo Fisher Scientific CCBE1 Polyclonal Antibody
CCBE1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간 단백질에 반응. 합성 펩타이드로 면역화되어 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human CCBE1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607192 |
Product Specific Information
Peptide sequence:
PMGPSPDLSH IKQGRRGPVG PPGAPGRDGS KGERGAPGPR GSPGPPGSFD
Sequence homology:
Cow: 100% | Dog: 100% | Guinea Pig: 100% | Human: 100% | Mouse: 100% | Rabbit: 100% | Rat: 100% | Zebrafish: 100%
Target Information
The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region frequently deleted in breast and prostate cancers.
CCBE1 is a 406 amino acid secreted protein containing two collagen-like domains and one calcium-binding EGF-like domain.
EGF-like domains typically include six cysteine residues forming disulfide bonds. Calcium-binding EGF-like domains may undergo amino acid substitutions that alter structure or calcium affinity, affecting protein function.
Downregulation of CCBE1 is often observed in breast cancer, suggesting a role in cell adhesion and motility as an extracellular protein.
Three isoforms of CCBE1 are produced through alternative splicing events.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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