Thermo Fisher Scientific Phospho-AMPK alpha-1,2 (Thr183, Thr172) Polyclonal Antibody
AMPK α1/α2 Thr183/Thr172 인산화 상태를 검출하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB와 ELISA에 최적화됨. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태, 연구용 전용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around T183 of human AMPKα1/AMPKα2 PRKAA1 (NP_0062425) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901888 |
Product Specific Information
- Positive Samples: 293T, C2C12, C6
- Immunogen Sequence: LRTSC
Target Information
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits.
It acts as an important energy-sensing enzyme that monitors cellular energy status.
Upon metabolic stress, AMPK is activated and phosphorylates key enzymes such as acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), regulating fatty acid and cholesterol biosynthesis.
Mouse studies indicate this subunit may control insulin sensitivity and maintain myocardial energy homeostasis during ischemia.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 파일명: PA5-117258_AMPK_alpha-1,2_Q13131-1_Rabbit.svg, PA5-117258_AMPK_alpha-1,2_P54646-1_Rabbit.svg, PA5-117258_AMPK_alpha-1,2_Q13131-1_Rabbit_PDP.jpeg, PA5-117258_AMPK_alpha-1,2_P54646-1_Rabbit_PDP.jpeg)
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