Thermo Fisher Scientific CYP4F11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CYP4F11. Recombinant protein control fragment (Product #RP-90473). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYP4F11,uniProtId:Q9HBI6-1,ncbiNodeId:9606,antigenRange:42-155,antigenLength:524,antigenImageFileName:PA5-53570_CYP4F11_Q9HBI6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53570_CYP4F11_Q9HBI6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640330

Product Specific Information

Immunogen sequence: YDNCRRLQCF PQPPKQNWFW GHQGLVTPTE EGMKTLTQLV TTYPQGFKLW LGPTFPLLIL CHPDIIRPIT SASAAVAPKD MIFYGFLKPW LGDGLLLSGG DKWSRHRRML TPAF

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%.

Target Information

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.