Thermo Fisher Scientific ALAS2 Polyclonal Antibody
Rabbit polyclonal antibody against human ALAS2 for WB and IHC(P) applications. Targets N-terminal peptide (aa 164–213). Protein A purified, liquid form, 1 mg/mL concentration. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human ALAS2 (aa 164–213) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609183 |
Product Specific Information
Peptide sequence:
VFKTVNRWAD AYPFAQHFSE ASVASKDVSV WCSNDYLGMS RHPQVLQATQ
Sequence homology:
Cow: 86%
Dog: 93%
Guinea Pig: 93%
Horse: 93%
Human: 100%
Mouse: 93%
Rabbit: 93%
Rat: 93%
Target Information
ALAS2 encodes an erythroid-specific, mitochondrially located enzyme that catalyzes the first step in the heme biosynthetic pathway.
Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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