Thermo Fisher Scientific C/EBP epsilon Polyclonal Antibody
C/EBP epsilon 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 핵 내 단백질 검출에 유용합니다. 고순도 Affinity Chromatography 정제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–190 of human CEBPE (NP_0017962) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.17 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805647 |
Product Specific Information
Immunogen sequence:
MSHGTYYECE PRGGQQPLEF SGGRAGPGEL GDMCEHEASI DLSAYIESGE EQLLSDLFAV KPAPEARGLK GPGTPAFPHY LPPDPRPFAY PPHTFGPDRK ALGPGIYSSP GSYDPRAVAV KEEPRGPEGS RAASRGSYNP LQYQVAHCGQ TAMHLPPTLA APGQPLRVLK APLATAAPPC SPLLKAPSPA
Positive Samples: Raji, Mouse liver, Rat liver
Cellular Location: Nucleus
Target Information
C/EBP alpha regulates gene expression in various tissues including liver, adipose, lung, and intestine. It uses a bipartite structural motif to bind DNA, where two protein chains dimerize through amphipathic alpha helices (leucine zipper). Basic polypeptide regions form DNA contact surfaces.
C/EBP alpha functions in terminally differentiated, growth-arrested cells. Family members include C/EBP beta, gamma, delta, and epsilon, all with similar DNA-binding specificities. C/EBP beta and delta can form heterodimers with each other and with C/EBP alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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