Thermo Fisher Scientific PON2 Polyclonal Antibody
PON2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 인간 반응성, 비결합형 액상 형태로 제공. 항산화 및 세포 방어 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–0.6 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EKPRARELRIS) corresponding to internal amino acids of PON2 (aa 93–104) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985615 |
Product Specific Information
- Predicted to react with canine, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
The PON2 gene encodes a member of the paraoxonase gene family, located on chromosome 7. The protein is membrane-bound and ubiquitously expressed in human tissues. It acts as a cellular antioxidant, protecting cells from oxidative stress. Its hydrolytic activity against acylhomoserine lactones suggests a role in defense against pathogenic bacteria. Mutations may be associated with vascular disease and diabetes-related phenotypes. Multiple alternatively spliced transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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