Thermo Fisher Scientific NUP93 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
IAERYRAQGI SANKFVDSTF YLLLDLITFF DEYHSGHIDR AFDIIERLKL VPLNQESVEE RVAAFRNFSD EIRHNLSEVL LATMNILFTQ FKRLKGTSPS SSSRPQRVIE DRDSQLRSQA RTLITFAGMI PYRTSGDTNA RLVQMEVLMN

Positive Samples:
U-87MG, A431, LO2, HeLa, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat testis

Cellular Location:
Nucleus, Nuclear membrane, Peripheral membrane protein, Nuclear pore complex

Target Information

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm.
Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells.
This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore.
The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis.
Alternative splicing results in multiple transcript variants encoding different isoforms.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.