Thermo Fisher Scientific BCL2L1 Polyclonal Antibody
BCL2L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스 등 다양한 종에 반응하며 WB, IHC, ICC, Flow, ELISA에 사용 가능. Protein A로 정제된 액상 항체로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:800 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Sheep, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human BCL2L1 (amino acids 81–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. These family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities. They are located at the outer mitochondrial membrane and regulate the opening of mitochondrial membrane channels (VDAC). This control affects mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release — key events in apoptosis.
Alternative splicing of the BCL-X gene produces two isoforms: the longer isoform acts as an apoptotic inhibitor, while the shorter isoform promotes apoptosis.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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