Thermo Fisher Scientific DNAJC1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
QWHDLLPCKL GIWFCLTLKA LPHLIQDAGQ FYAKYKETRL KEKEDALTRT

For short term use, store at 2–8°C up to 1 week.
For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology:
Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Target Information

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.
This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity.
These findings reveal a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.