Thermo Fisher Scientific Annexin A6 Polyclonal Antibody
Annexin A6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC(P)에서 사용 가능하며, 인간과 생쥐에 반응합니다. 액상 형태로 제공되며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Annexin A6 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 475–673 of Human Annexin VI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.179 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544938 |
Product Specific Information
- Recommended positive controls: H1299, NIH-3T3
- Predicted reactivity: Mouse (95%), Rat (95%), Chicken (80%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are not fully defined, several annexins are implicated in membrane-related events along exocytotic and endocytotic pathways.
The annexin VI gene (~60 kbp) contains 26 exons and encodes a ~68 kDa protein with eight 68-amino acid repeats separated by variable linker sequences. It is highly similar to human annexins I and II, each containing four repeats. Exon 21 of annexin VI is alternatively spliced, producing two isoforms differing by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI is implicated in endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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