Thermo Fisher Scientific PSMD8 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A549, HepG2
• Predicted reactivity: Mouse (92%), Rat (95%), Zebrafish (83%), Xenopus laevis (84%), Chimpanzee (100%), Bovine (95%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.

• The 20S core consists of four rings of 28 non-identical subunits (two alpha and two beta rings).
• The 19S regulator is composed of a base (six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
  Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
  A modified form, the immunoproteasome, processes class I MHC peptides.
  This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene is located on chromosome 1.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.