Thermo Fisher Scientific PKM2 Recombinant Rabbit Monoclonal Antibody (7V5X6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500 - 1:2,000

-

Immunoprecipitation (IP)

1:50-1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7V5X6

Immunogen

A synthesized peptide derived from human PKM2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PKM2,uniProtId:P14618-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:531,antigenImageFileName:MA5-42682_PKM2_P14618-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42682_PKM2_P14618-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911823

Product Specific Information

Positive test controls include: HeLa, 293T, A-549, NIH/3T3, C6, Mouse skeletal muscle, Mouse heart, Rat skeletal muscle. The target is usually found in the following locations: Cytoplasm, Nucleus.

Target Information

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.