Thermo Fisher Scientific PKM2 Recombinant Rabbit Monoclonal Antibody (7V5X6)
Recombinant rabbit monoclonal antibody targeting human PKM2, clone 7V5X6. Validated for WB and IP applications. Expressed in HEK293 cells, unconjugated form, 0.5 mg/mL concentration. Suitable for cytoplasmic and nuclear PKM2 detection in multiple cell ...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500 – 1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50 – 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7V5X6 |
| Immunogen | A synthesized peptide derived from human PKM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911823 |
Product Specific Information
Positive test controls include HeLa, 293T, A-549, NIH/3T3, C6, Mouse skeletal muscle, Mouse heart, and Rat skeletal muscle.
The target is typically localized in the cytoplasm and nucleus.
Target Information
PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP.
It interacts with thyroid hormone, mediating metabolic effects induced by thyroid hormones.
PKM2 also binds Opa protein, a bacterial outer membrane protein involved in gonococcal adherence and invasion of human cells, suggesting a role in bacterial pathogenesis.
Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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