Thermo Fisher Scientific GALR2 Polyclonal Antibody
GALR2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. 인간 반응성 확인 및 다양한 종에서 예측 반응성. Western blot 및 Peptide ELISA 검증 완료. 연구용으로만 사용 가능.
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- PA518630
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Thermo Fisher Scientific GALR2 Polyclonal Antibody
Applications
- Western Blot (WB): 0.3–1 µg/mL
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RYPLHSRELRTPRN) corresponding to the internal amino acids of GALR2 (aa 128–142) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985060 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:4000.
Target Information
GalR2 is widely expressed in the brain and peripheral tissues such as small intestine, heart, kidney, and liver.
Localization data from rat CNS indicate high expression in dorsal root ganglia, amygdala, and Purkinje neurons.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a seven-transmembrane domain structure.
They exist in active and inactive forms, with signaling mediated through G-proteins and downstream effectors.
Regulatory mechanisms affecting GPCR activity are crucial for cellular physiology and drug development.
Examples of GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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