Thermo Fisher Scientific IL1F9 Monoclonal Antibody (OTI2F4), TrueMAB
IL1F9 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 정제 및 안정적 액상 형태로 제공되며, 염증 반응 관련 연구용으로 최적화됨. 연구 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F4 |
| Immunogen | Full length human recombinant protein of human IL1F9 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor, activating NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system involved in epithelial barrier inflammatory responses, similar to the IL-1 system sharing the coreceptor IL1RAP. Plays a role in skin inflammation by acting on keratinocytes, dendritic cells, and T-cells to promote tissue infiltration and cell proliferation. Induces expression of various chemokines (CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CXCL8, CXCL1, CCL20) and proinflammatory factors (TNF-alpha, S100A7, inducible NOS). May contribute to airway inflammation and innate immune response to fungal pathogens such as Aspergillus fumigatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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