Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody (IGL/9397R)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

IGL/9397R

Immunogen

Recombinant fragment (around aa1-200) of human IGL protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Lambda light chain,uniProtId:P0CG04-1,ncbiNodeId:9606,antigenRange:1-106,antigenLength:106,antigenImageFileName:3535-RBM19-P0_Lambda_light_chain_P0CG04-1_Rabbit.svg,antigenImageFileNamePDP:3535-RBM19-P0_Lambda_light_chain_P0CG04-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:Lambda light chain,uniProtId:P01701-1,ncbiNodeId:9606,antigenRange:1-106,antigenLength:117,antigenImageFileName:3535-RBM19-P0_Lambda_light_chain_P01701-1_Rabbit.svg,antigenImageFileNamePDP:3535-RBM19-P0_Lambda_light_chain_P01701-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control: 293T Raji or hPBL cells. Human tonsil or spleen (IHC).

Cellular Location: Cell Surface. Cytoplasm. Secreted.

Target Information

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin`s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.