Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody (IGL/9397R)
인간 Lambda Light Chain을 표적으로 하는 재조합 토끼 단클론 항체로, B세포 마커 분석에 적합합니다. IHC(Paraffin)에서 1–2 µg/mL 농도로 사용 가능하며, HEK293 세포에서 발현되었습니다. Protein A/G로 정제된 액상 형태로, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody (IGL/9397R)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IGL/9397R |
| Immunogen | Recombinant fragment (around aa1–200) of human IGL protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: 293T, Raji, or hPBL cells; Human tonsil or spleen (IHC)
- Cellular Location: Cell surface, cytoplasm, secreted
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure consisting of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of approximately 22.5 kDa).
Kappa and lambda light chains consist of variable and constant regions, which can be differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is typically 70:30.
Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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