Thermo Fisher Scientific Human FNIP2 Synthetic Peptide
인간 FNIP2 단백질의 C-말단 16개 아미노산 서열에 해당하는 합성 펩타이드입니다. 폴리클로날 항체 PA5-20690의 블로킹 펩타이드로 사용 가능합니다. 액상 형태이며 PBS 버퍼에 보관, 연구용으로 적합합니다.
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Thermo Fisher Scientific Human FNIP2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human FNIP2.
PEP-0805 can be used as a blocking peptide with polyclonal antibody PA5-20690.
Target Information
FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin acts as a tumor suppressor, as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors.
Folliculin and FNIP1, which shares 49% identity with FNIP2, bind to AMPK, an important energy sensor that negatively regulates mTOR, the master switch for cell growth and proliferation. FNIP1 and FNIP2 can form homo- and heteromeric multimers, suggesting a functional relationship between these proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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