Thermo Fisher Scientific TPP1 Monoclonal Antibody (3B1)
TPP1 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ELISA에 적합. 인간 시료 반응성. PBS 용액 내 보존, 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B1 |
| Immunogen | TPP1 (AAH14863.1, 195 a.a. ~ 304 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GLHLGVTPSV IRKRYNLTSQ DVGSGTSNNS QACAQFLEQY FHDSDLAQFM RLFGGNFAHQ ASVARVVGQQ GRGRAGIEAS LDVQYLMSAG ANISTWVYSS PGRHEGQEPF
Target Information
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, associated with failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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