Thermo Fisher Scientific ART3 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: HeLa, NT2D1
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD⁺ to a specific amino acid in the target protein.
The rodent mono-ADP-ribosyltransferase RT6 is a GPI-anchored membrane protein expressed at the surface of rat and mouse T lymphocytes.
The predicted 367-amino acid human ART3 protein (≈41.5 kDa) contains:

• Hydrophobic peptide signal at N terminus
• Three consensus motifs for ADP-ribose transferase enzymes
• Hydrophobic C-terminal sequence typical of GPI-anchored proteins
• Novel motif repeated three times at C terminus
• One potential glycosylation site
  The ART3 and rodent RT6 proteins share 35% amino acid identity.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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