Thermo Fisher Scientific TFIP11 Polyclonal Antibody
Rabbit polyclonal antibody against human TFIP11, reactive with multiple species. Suitable for IHC and IHC (paraffin) applications. Purified by antigen affinity chromatography and supplied as liquid form. Recommended storage at 4°C, research use only.
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Thermo Fisher Scientific TFIP11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human tuftelin interacting protein 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
TFIP11 is involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover proceeds through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15, TFIP11 mediates the transition of the U2, U5, and U6 snRNP-containing IL complex to the snRNP-free IS complex, leading to efficient debranching and turnover of excised introns. It may also play a role in the differentiation of ameloblasts and odontoblasts or in the formation of the enamel extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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