Thermo Fisher Scientific COX8C Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Product Specifications

Product Specific Information

• Predicted to react with mouse samples.

Target Information

The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear.
The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle- and non-muscle-specific isoforms.
COX8 exists as three isoforms: COX8a (liver and heart), COX8b (heart-specific), and COX8c (expression pattern yet to be elucidated).
All three COX8 isoforms exist as components of the COX complex and play an important role in electron transport.
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.