Thermo Fisher Scientific COX8C Polyclonal Antibody
Rabbit polyclonal antibody against human COX8C, validated for Western blot. Predicted reactivity with mouse samples. Supplied as liquid, 1 mg/mL, stored at -20°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human COX8C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691853 |
Product Specific Information
- Predicted to react with mouse samples.
Target Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear.
The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle- and non-muscle-specific isoforms.
COX8 exists as three isoforms: COX8a (liver and heart), COX8b (heart-specific), and COX8c (expression pattern yet to be elucidated).
All three COX8 isoforms exist as components of the COX complex and play an important role in electron transport.
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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