Thermo Fisher Scientific Phospho-MARCKS (Ser167, Ser170) Recombinant Rabbit Monoclonal Antibody (MARCKSS167170-C9)
인간, 마우스, 랫트에 반응하는 recombinant rabbit monoclonal antibody. Ser167/170 인산화된 MARCKS 단백질 검출용. Western blot 및 유세포분석에 적합. Protein A/G 정제, PBS-BSA-glycerol buffer 보존. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MARCKSS167170-C9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.10% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897123 |
Additional Formats
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and functions as an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and the plasma membrane, resulting in cytoplasmic localization. This protein is implicated in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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