Thermo Fisher Scientific CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody (CD5/2418)
CD5 단백질을 인식하는 mouse monoclonal antibody로, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합. Mantle Cell Lymphoma 등 T세포 관련 질환 연구에 유용. 단백질 A/G 정제, PBS buffer, 무보존제 포뮬레이션. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mg |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CD5/2418 |
| Immunogen | Recombinant fragment of human CD5 protein (around aa 269–366) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
It is found on 95% of thymocytes and 72% of peripheral blood lymphocytes, with main reactivity in T-cell areas of lymph nodes. CD5 is expressed by many T-cell leukemias, lymphomas, and activated T cells.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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