Thermo Fisher Scientific AARS2 Polyclonal Antibody
AARS2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 Protein A 정제 및 안정한 보관 용액으로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human AARS2, amino acids 451–550 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The AARS2 gene encodes a mitochondrial alanyl-tRNA synthetase, a class-II aminoacyl-tRNA synthetase responsible for attaching alanine to tRNA(Ala) during protein synthesis. This enzyme plays a crucial role in mRNA translation and mitochondrial function. Mutations in AARS2 are associated with combined oxidative phosphorylation deficiency 8. The enzyme catalyzes a two-step reaction: activation of alanine by ATP to form Ala-AMP, followed by transfer to tRNA(Ala). It also corrects mischarged tRNA(Ala) through its editing domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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