Thermo Fisher Scientific Cdc7 Polyclonal Antibody
Cdc7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종에 반응하며 IHC(P)에서 6.5 µg/mL로 사용 가능. DNA 복제 및 세포주기 조절 연구에 적합. 고순도 항원 친화 크로마토그래피 정제 제품.
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Thermo Fisher Scientific Cdc7 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 6.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Human, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from kinase domain of human CDC7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550796 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum (100%).
Target Information
CDC7 is a cell division cycle 7 homolog protein critical for the G1/S transition and essential for initiation of DNA replication during cell division. It is expressed in many normal tissues, but overexpression may be associated with neoplastic transformation in some tumors and transformed cell lines.
CDC7/DBF4 kinase promotes S phase progression by alleviating inhibitory activity in Mcm4, integrating several protein kinases. Multiple alternatively spliced transcript variants encoding the same protein have been detected.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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