Thermo Fisher Scientific Stabilin 2 Monoclonal Antibody (OTI2A6)
Stabilin 2 단백질을 인식하는 마우스 단클론 항체로, IHC(P)에서 1:150 희석으로 검증됨. 인간 시료에 반응하며, 액상 형태로 제공되고 -20°C에서 보관. 혈관신생 및 세포 부착 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1914–2194 of STAB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725432 |
Target Information
This gene encodes a large transmembrane receptor protein that may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging.
The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains, as well as a C-type lectin-like hyaluronan-binding Link module.
It is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node.
The receptor binds and endocytoses ligands such as hyaluronan, low-density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products, supporting its role as a scavenger receptor cycling between the plasma membrane and lysosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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