Thermo Fisher Scientific MAP4K4/HGK Polyclonal Antibody
MAP4K4/HGK 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 액상 형태로 제공되며 4°C에서 보관합니다. 스트레스 반응 관련 MAPK 신호 경로 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 550 and 600 of human MAPK/ERK kinase kinase kinase 4 (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
MAP4K4 (HGK) is a serine/threonine kinase involved in stress-activated MAPK signaling pathways and response to environmental stress and cytokines such as TNF-alpha. It acts upstream of the JUN N-terminal pathway and interacts with the SH3 domain of adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression is ubiquitous across tissue types; isoform 5 is more abundant in the brain, while isoform 4 predominates in liver, skeletal muscle, and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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