Thermo Fisher Scientific EphB4 Recombinant Rabbit Monoclonal Antibody (001)

Applications and Tested Dilution

Product Specifications

Available Conjugated Formats

• APC
• FITC
• PE
• Request custom conjugation

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select optimal candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Human EphB4/Eph Receptor B4.

Target Information

EPHB4 is a receptor tyrosine kinase belonging to the ephrin receptor family. Eph kinases play crucial roles in nervous system development, angiogenesis, and synapse formation. Ephrin ligands are divided into ephrin-A (EFNA) and ephrin-B (EFNB) classes, with Eph receptors grouped accordingly based on extracellular domain similarities and ligand affinities.

Ephrin receptors represent the largest subgroup of receptor tyrosine kinases (RTKs). EphB4 binds to ephrin-B2 and is essential for vascular development.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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