Thermo Fisher Scientific CHI3L1 Polyclonal Antibody
CHI3L1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(PFA)에서 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제되었으며 PBS와 50% glycerol에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CHI3L1 (Accession P36222), corresponding to amino acid residues A251–D301 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899649 |
Product Specific Information
This antibody detects endogenous levels of total CHI3L1.
Target Information
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes, and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells, and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and plays a role in the cellular response to environmental changes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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