Thermo Fisher Scientific MYOZ1 Polyclonal Antibody
MYOZ1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며, 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYOZ1 (Accession Q9NP98), corresponding to amino acid residues T239–G289 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850136 |
Product Specific Information
This antibody detects endogenous levels of total MYOZ1.
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. Titin serves as a scaffold for myofibrils and other muscle-related proteins.
The MYOZ1 gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1–Z2 domains and is a substrate of titin kinase, interactions thought to be critical for sarcomere assembly.
Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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