Thermo Fisher Scientific NCOA6 Polyclonal Antibody
NCOA6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot 및 IHC(P)에서 사용 가능하며, 인간, 마우스, 랫트 반응성. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NCOA6 (Accession Q14686), corresponding to amino acid residues S884–D934 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850139 |
Product Specific Information
Antibody detects endogenous levels of total NCOA6.
Target Information
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates transcriptional activities in a hormone-dependent fashion.
Coactivates expression in an agonist- and AF2-dependent manner.
Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR), and prostanoids (PPARs).
Probably functions as a general coactivator, rather than just a nuclear receptor coactivator.
May also be involved in the coactivation of the NF-kappa-B pathway.
May coactivate expression via chromatin remodeling and interaction with histone acetyltransferase proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-100633_NCOA6_Q14686-1_Rabbit_PDP.jpeg)
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