Thermo Fisher Scientific KIRREL2 Polyclonal Antibody
KIRREL2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western Blot과 ELISA에 사용 가능하며, 고순도의 Affinity Chromatography 정제 항체입니다. 세포막 단백질 연구 및 당뇨병 관련 연구에 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–220 of human KIRREL2 (NP_9546493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.9 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805294 |
Product Specific Information
Immunogen sequence:
GPSPHFLQQP EDLVVLLGEE ARLPCALGAY WGLVQWTKSG LALGGQRDLP GWSRYWISGN AANGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL VPPEAPQVLG GPSVSLVAGV PANLTCRSRG DARPTPELLW FRDGVLLDGA TFHQTLLKEG TPGSVESTLT LTPFSHDDGA TFVCRARSQA LPTGRDTAIT
Positive Samples: Mouse kidney, Rat kidney
Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
This gene encodes a type I transmembrane protein and a member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against this protein have been detected in serum from patients with type 1 diabetes. It may also play a role in glomerular development, and decreased expression has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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