Thermo Fisher Scientific KIRREL2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human KIRREL2 (NP_9546493) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KIRREL2,uniProtId:Q6UWL6-1,ncbiNodeId:9606,antigenRange:21-220,antigenLength:708,antigenImageFileName:PA5-89009_KIRREL2_Q6UWL6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89009_KIRREL2_Q6UWL6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4.9 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805294

Product Specific Information

Immunogen sequence: GPSPHFLQQP EDLVVLLGEE ARLPCALGAY WGLVQWTKSG LALGGQRDLP GWSRYWISGN AANGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL VPPEAPQVLG GPSVSLVAGV PANLTCRSRG DARPTPELLW FRDGVLLDGA TFHQTLLKEG TPGSVESTLT LTPFSHDDGA TFVCRARSQA LPTGRDTAIT; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein

Target Information

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.