Thermo Fisher Scientific TSLP Polyclonal Antibody
Human, Mouse, Rat에 반응하는 TSLP 폴리클로날 항체로 Western blot, ICC/IF, ELISA에 적합. Rabbit IgG로 제작되었으며, Affinity Chromatography로 정제됨. PBS와 50% glycerol buffer에 보관되며 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 29–159 of human TSLP (NP_149024.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.92 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805297 |
Product Specific Information
Immunogen sequence:
YDFTNCDFEK IKAAYLSTIS KDLITYMSGT KSTEFNNTVS CSNRPHCLTE IQSLTFNPTA GCASLAKEMF AMKTKAALAI WCPGYSETQI NATQAMKKRR KRKVTTNKCL EQVSQLQGLW RRFNRPLLKQ Q
Positive Samples: U-87MG, Rat brain
Target Information
TSLP is a 159 amino acid four-helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c(+) dendritic cells, naive CD4(+) and CD8(+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation.
TSLP influences the regulation of regulatory T cell selection and maintenance of peripheral CD4(+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in inflammatory arthritis. It is expressed in heart, liver, and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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