Thermo Fisher Scientific DYRK1A Polyclonal Antibody
DYRK1A 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot과 면역침전(IP)에 적합하며, 모든 DYRK1A isoform을 인식. 액상 형태로 제공되며 TBS buffer에 0.5% BSA 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence: PHSHQYSDRRQPN-C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933528 |
Product Specific Information
- Recognizes all reported isoforms (NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1).
- Not expected to cross-react with DYRK1B.
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21 and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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