Thermo Fisher Scientific WWP1 Monoclonal Antibody (1A7)
WWP1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 사용 가능. 인간 유래 단백질에 반응하며, PBS 완충액에 보존된 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A7 |
| Immunogen | WWP1 (NP_008944, 152 a.a. – approximately 260 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
CSSSPTIEIQ ENGDALHENG EPSARTTARL AVEGTNGIDN HVPTSTLVQN SCCSYVVNGD NTPSSPSQVA ARPKNTPAPK PLASEPADDT VNGESSSFAP TDNASVTGT
Target Information
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing.
This gene encodes a protein which contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain.
The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules that regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.
Alternative splicing of this gene generates at least six transcript variants; however, the full-length nature of these transcripts has not been defined.
[provided by RefSeq]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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