Thermo Fisher Scientific MRPL23 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MRPL23. Recombinant protein control fragment (Product #RP-100653). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MRPL23,uniProtId:Q16540-1,ncbiNodeId:9606,antigenRange:78-153,antigenLength:153,antigenImageFileName:PA5-62184_MRPL23_Q16540-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62184_MRPL23_Q16540-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644134

Product Specific Information

Immunogen sequence: KRRDHRNVRI KKPDYKVAYV QLAHGQTFTF PDLFPEKDES PEGSAADDLY SMLEEERQQR QSSDPRRGGV PSWFGL

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 74%.

Target Information

MRPL23 are mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL23 encodes a 39S subunit protein and is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.